John Maher

John Maher

Company: & Senior Lecturer in Immunology Kings College London

Job title: CSO, Leucid Bio


Phase I Evaluation of T4 CAR T-Cell Immunotherapy of Locally Advanced/Recurrent Head and Neck Cancer 1:00 pm

 T4 immunotherapy consists of autologous T-cells that co- express a Pan-ErbB targeted CAR (T1E28z) and an IL-4 responsive chimeric cytokine receptor, 4ab Cell products are manufactured from a blood draw in a 2 week closed GMP process, using IL-4 to drive expansion of transduced cells Sixteen patients have received intra-tumoural T4 CAR T-cells at doses…Read more

day: Day Two

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